BROUSSOCHALCONE A IS A NOVEL INHIBITOR OF THE ORPHAN NUCLEAR RECEPTOR NR4A1 AND INDUCES APOPTOSIS IN PANCREATIC CANCER CELLS

Broussochalcone A Is a Novel Inhibitor of the Orphan Nuclear Receptor NR4A1 and Induces Apoptosis in Pancreatic Cancer Cells

The orphan nuclear receptor 4A1 (NR4A1) is overexpressed in pancreatic cancer and exhibits pro-oncogenic activity, and NR4A1 silencing and treatment with its inactivators has been shown to inhibit pancreatic cancer cells and tumor growth.In this study, we identified broussochalcone A (BCA) as a new NR4A1 inhibitor and demonstrated that BCA inhibits

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Contemporary Documentary in Taiwan: Memory, Identity, Flux

In the following paper I will seek to illustrate how four documentaries made in recent years by young Taiwanese filmmakers, Le Moulin (2015), Wansei Painter - Tetsuomi Tateishi (2016), Letter #69 (2016) and 3 Islands (2015), display a fresh and original approach in the landscape of contemporary non-fiction cinema both on the island and in Southeast

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Analyzing EZproxy SPU Logs Using Python Data Analysis Tools

Even with the Ball - Umpire assortment of free and ready-made tools for analyzing EZproxy log files, it can be difficult to get useful, meaningful data from them.Using the Python programming language with its collection of modules created specifically for data analysis can help with this task, and ultimately result in better Ladders and more useful

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A practice-based trial of blood pressure control in African Americans (TLC-Clinic): study protocol for a randomized controlled trial

Abstract Background Poorly controlled hypertension (HTN) remains one of the most significant public health problems in the United States, in terms of morbidity, mortality, and economic burden.Despite compelling evidence supporting the beneficial effects of therapeutic lifestyle changes (TLC) for blood pressure (BP) reduction, the effectiveness of t

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